Wednesday, October 27, 2010

RA

Institute of Life Sciences
University of Hyderabad Campus
Gachibowli
Hyderabad-500 046

Position of a Research Associate to Work on the DST Sponsored Organic Synthesis Project @ Institute of Life Sciences (ILS), Hyderabad

Applications are invited for the following Research Associate position in Computer-Aided Drug Discovery (CADD) group to work on the DST funded project, “Design, Synthesis, and Biological Evaluation of Pharmaceuticallly Acceptable PTP-1B inhibitors”.

Interested candidates should send their curriculum vitae with a cover letter via e-mail to hr@ilsresearch.org and sreedhara.voleti@ilsresearch.org no later than 30th October, 2010.

Suitable candidates will be invited for an interview at the Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad – 500046. The location of the work is full-time at the ILS.

Research Associate Fellowship:

Rs 22000 (basic) + 6600 (HRA) + 1833 (MR) = Rs 30433 (fixed per month) inclusive all benefits for two years.

Duration: TWO year fixed from the date of joining

Responsibilities: The candidate will be performing molecular modeling studies assigned in the project - designing, validating, and analyzing

(a) SAR activities (b) protein-ligand interactions in collaboration with the medicinal chemists and molecular biologists/pharmacologists. Main responsibilities include computational studies and rational drug discovery applications. These studies also include literature search, proper design and performing documentation, report and presentation generation etc.

Essential Qualifications:

(A) Ph.D. from a recognized university/institute in Computational Chemistry/Biology with drug discovery principles as part of research work, or
(B) Masters with Pharmacy or Science (organic/physical chemistry) from a recognized university/institute with a minimum 3-year research experience in relevant molecular modeling applications in drug discovery setting is minimally required. Extensive applicative/usage knowledge in any drug discovery packages such as BioSuite, Discovery Studio, GOLD, MDS, MOE, Schrodinger, SYBYL, MDS, and Sybyl is highly essential; and, working experience with other cheminformatics packages like ACD/Labs etc. is highly desirable. Working in team-environment with high morale is essential.

Experience in evaluation of protein-ligand interactions through docking, scoring, QSAR, SAR methods is essential. Educational or applied synthetic organic chemistry knowledge with reaction mechanisms is beneficial.

Candidate should have extensive proficiency with Unix, Linux, Windows operating systems, MS office products, and should be able to troubleshoot the HW/SW issues. He/She would be involved in training medicinal chemists or early stage molecular modelers of the group in computational aspects.

Research Experience: More than 3 years with Masters’ degree or Ph.D in computer aided drug discovery.

Notes:

• Visit the ILS website (whttp://www.ilsresearch.org/) to obtain in-depth information about the institute
• Applicants should note that the appointments are purely temporary and there will be no right to claim for any regular appointment
• The initial appointment will be made for one year and this could further be extended to one more year based on the work progress
• No TA/DA will be paid to participate in the interview process or to join the institute.

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